Co-operative double-blind trial of an antibiotic/corticoid combination in impetiginized atopic dermatitis

Br J Dermatol. 1976 Sep;95(3):323-8. doi: 10.1111/j.1365-2133.1976.tb07021.x.


This double-blind study of an antibiotic coritcosteroid combination, the antibiotic alone and the corticosteroid alone, compared their clinical and microbiological effect in infected atopic dermatitis. Combination therapy reduced the mean scores for infection, inflammation and overall severity to a greater extent than the antibiotic or corticosteroid alone. The clinical and microbiological date are discussed in terms of relevance to clinical use.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Bacteria / isolation & purification
  • Betamethasone / analogs & derivatives*
  • Betamethasone Valerate / administration & dosage*
  • Betamethasone Valerate / therapeutic use
  • Clinical Trials as Topic
  • Dermatitis, Atopic / drug therapy*
  • Dermatitis, Atopic / microbiology
  • Drug Combinations
  • Gentamicins / administration & dosage*
  • Gentamicins / therapeutic use
  • Humans


  • Drug Combinations
  • Gentamicins
  • Betamethasone
  • Betamethasone Valerate