Spinal pattern generation

Curr Opin Neurobiol. 1994 Dec;4(6):894-902. doi: 10.1016/0959-4388(94)90139-2.


Recent research in the field of spinal pattern generation has concentrated on three main areas: the effects of various transmitters on spinal rhythmic patterns in reduced preparations (neonatal rats, chick embryos, tadpole embryos, lampreys); the changes in membrane properties of different elements of the generating circuits; and the interactions between central generating mechanisms and afferent inputs. The important message is that new properties of neural membranes, as well as new reflex responses, have been identified that could not have been predicted in the absence of such rhythmic activity.

Publication types

  • Review

MeSH terms

  • Afferent Pathways / physiology*
  • Animals
  • Cats
  • Chick Embryo
  • Dopamine / physiology
  • Lampreys / physiology
  • Locomotion / physiology
  • Motor Activity / physiology*
  • Motor Neurons / physiology
  • Movement / physiology
  • Neurotransmitter Agents / physiology*
  • Norepinephrine / physiology
  • Rats
  • Serotonin / physiology
  • Spinal Cord / physiology*


  • Neurotransmitter Agents
  • Serotonin
  • Dopamine
  • Norepinephrine