Production of migration inhibitory factor and lymphotoxin by non-T cells

Eur J Immunol. 1975 Mar;5(3):218-20. doi: 10.1002/eji.1830050314.

Abstract

Treatment of tuberculin-sensitive guinea pig spleen or lymph node cells with a burro anti-T cell serum plus complement diminished markedly the number of functionally detectable T cells, but did not affect the amount of migration inhibitory factor (MIF) or lymphotoxin produced by the residual T cell-depleted populations.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Antilymphocyte Serum
  • Guinea Pigs
  • In Vitro Techniques
  • Lymph Nodes / immunology
  • Lymphocytes / immunology*
  • Lymphocytes / metabolism
  • Lymphotoxin-alpha / biosynthesis*
  • Macrophage Migration-Inhibitory Factors / biosynthesis*
  • Spleen / immunology
  • T-Lymphocytes / immunology
  • Tuberculin

Substances

  • Antilymphocyte Serum
  • Lymphotoxin-alpha
  • Macrophage Migration-Inhibitory Factors
  • Tuberculin