Abstract
Ten patients, who underwent computerized tomography (CT) study during evaluation for first episode schizophreniform psychosis were restudied an average of 7 years later. Of the 10 patients, 7 were found to carry a diagnosis of schizophrenia at follow-up. In this subgroup, there was no significant change in the mean ventricular brain ratio measure of cerebral ventricular size between the index and follow-up scans. These findings are consistent with the hypothesis that ventricular enlargement is present at the onset of schizophrenia and does not progress with duration of illness or treatment.
MeSH terms
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Adolescent
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Adult
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Antipsychotic Agents / therapeutic use
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Bipolar Disorder / diagnosis
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Bipolar Disorder / drug therapy
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Bipolar Disorder / psychology
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Brain / drug effects
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Brain / pathology
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Cerebral Ventricles / drug effects
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Cerebral Ventricles / pathology*
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Chronic Disease
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Cohort Studies
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Female
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Follow-Up Studies
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Humans
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Hypertrophy / pathology
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Male
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Patient Readmission
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Psychiatric Status Rating Scales
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Psychotic Disorders / diagnosis*
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Psychotic Disorders / drug therapy
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Psychotic Disorders / psychology
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Schizophrenia / diagnosis
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Schizophrenia / drug therapy
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Schizophrenic Psychology
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Tomography, X-Ray Computed*