[The problems of spotted breeds of rabbits. 4. Morpho- and histometric findings in the CNS and thyroid glands and the hormone content in blood at slaughter of hybrid rabbits, and estimation of the heterosis effect]

Dtsch Tierarztl Wochenschr. 1994 Nov;101(11):434-9.
[Article in German]


Morpho- und histometric investigations of brains, pituitary and thyroid glands as well as thyroid-related functional parameters in the blood of purebred and hybrid rabbits revealed a predisposition to hypothyreotic conditions in homozygous, megacolon-prone genotypes. In addition to this also a hypoganglionotic state in different gut wall localizations was confirmed; pituitary traits however did not indicate a primary contribution of this gland to the syndrome, though some alterations were found, which are interpreted as secondary sv. symptomatic. Gender influences varied hormonal characteristics and disease manifestations too: A dramatic fall in severely diseased does with respect to T3-concentration as well as a seemingly more inactive thyroid gland compared to bucks underline hormonal influences. As a consequence of these results it is concluded, that hybridisation within spotted rabbits does not amend the inclination to megacolon in animals homozygous for the K (En) gene, though it may influence its manifestation.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Brain / anatomy & histology*
  • Crosses, Genetic*
  • Female
  • Hirschsprung Disease / genetics
  • Hirschsprung Disease / veterinary
  • Hybrid Vigor*
  • Male
  • Pituitary Gland / anatomy & histology
  • Pituitary Gland / physiology
  • Rabbits* / genetics
  • Thyroid Gland / anatomy & histology*
  • Thyroid Gland / physiology
  • Thyroid Hormones / blood


  • Thyroid Hormones