Efficacy of ivermectin for the treatment of head lice (Pediculosis capitis)

Trop Med Parasitol. 1994 Sep;45(3):253-4.

Abstract

Twenty six male and female patients aged 5 to 17 years who had head lice infestation confirmed by eggs presence and received treatments with a single 200 mu/kg oral dose of ivermectin in open fashion. At day 14 after treatment, 20 responded to the treatment (77%), and 6 patients (23%) presented with a complete disappearance of eggs and all clinical symptoms. At day 28, 7 patients were healed (27%), but 4 patients of the 6 healed at day 14 presented with signs of reinfestation. This study suggests that ivermectin is a promising treatment of head lice, and a second dose at day 10 should be appropriate for a further comparative trial.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Ivermectin / therapeutic use*
  • Lice Infestations / drug therapy*
  • Male
  • Pilot Projects
  • Scalp Dermatoses / drug therapy*

Substances

  • Ivermectin