Glucose repression in fungi

Trends Genet. 1995 Jan;11(1):12-7. doi: 10.1016/s0168-9525(00)88980-5.


In many organisms, glucose represses genes that are used to metabolize other carbon sources. Work in yeast and filamentous fungi has revealed a mechanism for glucose repression in eukaryotes that is different from that found in bacteria. Zinc finger proteins, such as Mig1 and CREA, that bind GC-boxes play a key role in mediating this response.

Publication types

  • Review

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Fermentation
  • Fungi / genetics
  • Fungi / growth & development
  • Fungi / metabolism*
  • Gene Expression Regulation, Fungal*
  • Genes, Fungal*
  • Glucose / metabolism*
  • Models, Biological
  • Molecular Sequence Data
  • Sequence Homology, Amino Acid


  • Glucose