Bronchial reactivity and work-related symptoms in farmers

Am J Ind Med. 1995 Jan;27(1):65-74. doi: 10.1002/ajim.4700270107.


Work-related respiratory symptoms and bronchial reactivity were studied in 76 never-smoking farmers and in a control group not exposed to organic dusts. The farmers were divided into those working with vegetables/grain crops, animals but not swine, and with swine. The extent of symptoms was evaluated using a specific organic dust questionnaire. Bronchial reactivity was assessed with the methacholine challenge test. An increased incidence of organic dust toxic syndrome (ODTS), mucous membrane irritation (MMI), and chronic bronchitis (CB) was found among farmers working with swine or other animals. Pulmonary function baseline values were normal. Bronchial reactivity was increased and related to subjective symptoms of MMI and CB. There was also a relation between fatigue at work and bronchial reactivity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Agriculture*
  • Animals
  • Animals, Domestic
  • Bronchial Hyperreactivity / etiology*
  • Bronchial Hyperreactivity / physiopathology
  • Bronchial Provocation Tests
  • Bronchitis / complications
  • Chronic Disease
  • Dust / adverse effects
  • Edible Grain
  • Fatigue / complications
  • Female
  • Humans
  • Male
  • Methacholine Chloride
  • Middle Aged
  • Occupational Diseases / etiology*
  • Occupational Diseases / physiopathology
  • Occupational Exposure*
  • Sweden
  • Swine
  • Syndrome
  • Vegetables


  • Dust
  • Methacholine Chloride