Expressed sequence tags identify a human isolog of the suil translation initiation factor

Biochem Biophys Res Commun. 1994 Jan 14;198(1):288-91. doi: 10.1006/bbrc.1994.1040.

Abstract

The complete cDNA sequence of a human isolog of the yeast suil translation initiation factor gene was obtained by assembling over 40 expressed sequence tags (ESTs) for this gene obtained from a variety of tissue-specific cDNA libraries. The human suilisol gene product is a 113 amino-acid polypeptide similar to proteins known from yeast, rice, mosquito, and Methanococcus. The identification of suilisol illustrates the utility of assemblies of independent ESTs for deriving full-length cDNA sequences for new human genes.

Publication types

  • Comparative Study

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Culicidae / genetics
  • DNA, Complementary / analysis
  • DNA, Complementary / chemistry
  • DNA, Complementary / genetics*
  • Eukaryotic Initiation Factor-1
  • Fungal Proteins / genetics*
  • Gene Expression
  • Gene Library
  • Genes, Fungal*
  • Hominidae / genetics*
  • Humans
  • Methanococcus / genetics
  • Molecular Sequence Data
  • Open Reading Frames
  • Oryza / genetics
  • Peptide Initiation Factors / genetics*
  • Saccharomyces cerevisiae / genetics*
  • Saccharomyces cerevisiae Proteins*
  • Sequence Homology, Amino Acid

Substances

  • DNA, Complementary
  • Eukaryotic Initiation Factor-1
  • Fungal Proteins
  • Peptide Initiation Factors
  • SUI1 protein, S cerevisiae
  • Saccharomyces cerevisiae Proteins

Associated data

  • GENBANK/L26247