Lithium treatment of meniere's disease. Results of a double-blind cross-over trial

Acta Otolaryngol. 1976 Sep-Oct;82(3-4):294-6. doi: 10.3109/00016487609120909.


21 patients with Meniere's disease participated in a double-blind, cross-over trial, with 6 months' lithium treatment and 6 months' placebo treatment. Even if the results were not completely unequivocal, no difference was found between lithium and placebo treatment. The results might imply that both other medical as well as surgical treatment of Meniere's disease exert a pure placebo effect; so far no controlled investigation has been published, establishing the value of surgical treatment of Meniere's disease.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Clinical Trials as Topic
  • Drug Evaluation
  • Humans
  • Lithium / therapeutic use*
  • Meniere Disease / drug therapy*
  • Placebos


  • Placebos
  • Lithium