CD26: a surface protease involved in T-cell activation

Immunol Today. 1994 Apr;15(4):180-4. doi: 10.1016/0167-5699(94)90316-6.


CD26 is a proteolytic enzyme (dipeptidylpeptidase IV) with a wide tissue distribution and a unique specificity. Recent developments indicate that CD26 is a multifunctional molecule that may have important functions in the immune system. Here, Bernhard Fleischer reviews the current knowledge of CD26 and discusses the possible functions of this molecule in T lymphocytes.

Publication types

  • Review

MeSH terms

  • Antigens, Differentiation, T-Lymphocyte / immunology*
  • Cell Differentiation / physiology
  • Dipeptidyl Peptidase 4
  • Dipeptidyl-Peptidases and Tripeptidyl-Peptidases / immunology*
  • HIV / immunology
  • Humans
  • Lymphocyte Activation / physiology*
  • T-Lymphocytes / physiology*


  • Antigens, Differentiation, T-Lymphocyte
  • Dipeptidyl-Peptidases and Tripeptidyl-Peptidases
  • Dipeptidyl Peptidase 4