Abstract
Skin rash is a common side effect of sulphasalazine. Desensitisation, with a gradual introduction of the drug, may prevent rash. This study reports a 33% (3/9 patients) success rate of desensitisation in patients with arthritis. Desensitisation should only be attempted if sulphasalazine has been efficacious in treating the joint symptoms.
MeSH terms
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Adult
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Aged
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Arthritis, Juvenile / drug therapy*
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Arthritis, Psoriatic / drug therapy*
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Arthritis, Rheumatoid / drug therapy*
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Desensitization, Immunologic*
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Drug Eruptions / etiology*
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Drug Eruptions / immunology
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Female
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Humans
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Male
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Middle Aged
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Sulfasalazine / adverse effects*
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Sulfasalazine / immunology
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Sulfasalazine / therapeutic use