Temperature dependence of synaptic modulation by a FMRFamide-related neuropeptide in crayfish

Neurosci Lett. 1994 Mar 14;169(1-2):56-8. doi: 10.1016/0304-3940(94)90355-7.


The present study examined the temperature dependence of synaptic transmission and peptidergic modulation of chemical synapses on the phasic abdominal extensor muscles of crayfish. Decreasing the temperature from 25 degrees C to 5 degrees C in saline, decreased the EPSP amplitude by 88% and increased the EPSP half-decay time four-fold. The putative neurohormone DRNFLRFamide (DF2) increased EPSP amplitudes, but was more effective at 7-9 degrees C than at 15-17 degrees C. DF2 might play a hormonal role in counteracting low transmitter release at low temperature.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Astacoidea / physiology*
  • Evoked Potentials / physiology
  • FMRFamide
  • Molecular Sequence Data
  • Muscles / innervation
  • Muscles / physiology
  • Neuropeptides / physiology*
  • Neurotransmitter Agents / physiology*
  • Synapses / physiology*
  • Temperature


  • Neuropeptides
  • Neurotransmitter Agents
  • neuropeptide DF2
  • FMRFamide