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. 1994 Sep 14;1194(2):349-51.
doi: 10.1016/0005-2736(94)90319-0.

Sequence of a Putative Transporter From Rabbit Kidney Related to the Na+/glucose Cotransporter Gene Family

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Sequence of a Putative Transporter From Rabbit Kidney Related to the Na+/glucose Cotransporter Gene Family

A M Pajor. Biochim Biophys Acta. .

Abstract

A 2 kb cDNA, RK-D, was isolated from a rabbit renal library by hybridization with the Na+/glucose cotransporter (SGLT1) cDNA. The mRNA for RK-D is also approximately 2 kb and is found predominantly in kidney. The RK-D cDNA encodes a protein of 597 amino acids related in sequence to the SGLT family of sodium-coupled transporters, all of which are related to the Na+/glucose cotransporter, SGLT1. Because of the high sequence similarity and conservation of 'signature' family features, it is very likely that RK-D encodes a Na(+)-dependent cotransporter.

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