Effect of decaffeination of coffee or tea on gastro-oesophageal reflux

Aliment Pharmacol Ther. 1994 Jun;8(3):283-7. doi: 10.1111/j.1365-2036.1994.tb00289.x.


Background: Coffee and tea are believed to cause gastro-oesophageal reflux; however, the effects of these beverages and of their major component, caffeine, have not been quantified. The aim of this study was to evaluate gastro-oesophageal reflux induced by coffee and tea before and after a decaffeination process, and to compare it with water and water-containing caffeine.

Methods: Three-hour ambulatory pH-metry was performed on 16 healthy volunteers, who received 300 ml of (i) regular coffee, decaffeinated coffee or tap water (n = 16), (ii) normal tea, decaffeinated tea, tap water, or coffee adapted to normal tea in caffeine concentration (n = 6), and (iii) caffeine-free and caffeine-containing water (n = 8) together with a standardized breakfast.

Results: Regular coffee induced a significant (P < 0.05) gastro-oesophageal reflux compared with tap water and normal tea, which were not different from each other. Decaffeination of coffee significantly (P < 0.05) diminished gastro-oesophageal reflux, whereas decaffeination of tea or addition of caffeine to water had no effect. Coffee adapted to normal tea in caffeine concentration significantly (P < 0.05) increased gastro-oesophageal reflux.

Conclusions: Coffee, in contrast to tea, increases gastro-oesophageal reflux, an effect that is less pronounced after decaffeination. Caffeine does not seem to be responsible for gastro-oesophageal reflux which must be attributed to other components of coffee.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Caffeine*
  • Coffee*
  • Female
  • Gastroesophageal Reflux / etiology*
  • Humans
  • Male
  • Random Allocation
  • Tea*
  • Water


  • Coffee
  • Tea
  • Water
  • Caffeine