Chorionic gonadotropin in weight control. A double-blind crossover study

JAMA. 1976 Nov 29;236(22):2495-7.


Two hundred two patients participated in a double-blind random cross-over study of the effectiveness of human chorionic gonadotropin (HCG) vs placebo in a wieght reduction program. Serial measurements were made of weight, skin-fold thickness, dropout rates, reasons for dropping out, and patient subjective response. There was no statistically significant difference between those receiving HCG vs placebo during any phase of this study (P greater than .1).

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Body Weight / drug effects*
  • Chorionic Gonadotropin / administration & dosage
  • Chorionic Gonadotropin / pharmacology*
  • Chorionic Gonadotropin / therapeutic use
  • Clinical Trials as Topic
  • Diet, Reducing
  • Drug Evaluation
  • Female
  • Humans
  • Injections
  • Male
  • Obesity / diet therapy
  • Obesity / drug therapy*


  • Chorionic Gonadotropin