Intraocular gentamicin sulfate and postcataract anterior chamber aspirate cultures

J Cataract Refract Surg. 1994 Jul;20(4):373-7. doi: 10.1016/s0886-3350(13)80169-1.

Abstract

We cultured anterior chamber aspirates of 28 patients who had uncomplicated cataract surgery. Fourteen patients had received 80 micrograms/ml of gentamicin in balanced salt solution through irrigation of the anterior chamber throughout cataract extraction, and 14 patients had received 8 micrograms/ml of gentamicin. Cultures of anterior chamber fluid obtained at the end of surgery from all 28 patients had no growth on two nonselective media. There was no clinical evidence of ocular toxicity. This study demonstrates that antibiotic in the intraocular irrigation fluid can reduce or eliminate the expected intraocular bacterial load after cataract surgery.

MeSH terms

  • Anterior Chamber / microbiology*
  • Aqueous Humor / microbiology
  • Cataract Extraction*
  • Drainage
  • Endophthalmitis / microbiology
  • Endophthalmitis / prevention & control
  • Eye Infections, Bacterial / diagnosis
  • Eye Infections, Bacterial / prevention & control*
  • Gentamicins / therapeutic use*
  • Humans
  • Isotonic Solutions
  • Lenses, Intraocular
  • Premedication*
  • Therapeutic Irrigation
  • Visual Acuity

Substances

  • Gentamicins
  • Isotonic Solutions