The use of amniotic membrane plus heparin to prevent postoperative adhesions in the rabbit

Tokai J Exp Clin Med. 1993 Jun;18(1-2):57-60.


Fifteen female rabbits which were divided into three groups were used in this study. Amniotic membrane with or without heparin was used to cover experimentally injured uterine horns. Four weeks later all animals underwent second laparotomy and adhesion formation was examined. Our data showed that amniotic membrane plus heparin was an effective combination in reducing adhesion formation.

MeSH terms

  • Amnion / transplantation*
  • Animals
  • Disease Models, Animal
  • Female
  • Heparin / pharmacology*
  • Postoperative Complications / prevention & control*
  • Pregnancy
  • Rabbits
  • Tissue Adhesions / prevention & control*
  • Transplantation, Homologous
  • Uterus / injuries
  • Uterus / surgery


  • Heparin