[Immunomodulatory function of polysaccharide of Hericium erinaceus]

Zhongguo Zhong Xi Yi Jie He Za Zhi. 1994 Jul;14(7):427-8.
[Article in Chinese]


Hericium erinaceus is a Chinese herbal medicine. The Apollo oral liquid contains polysaccharide of H. erinaceus (PHE). The effects of PHE on proliferation of mice T and B lymphocytes were studied. Results showed that (1) 3-fold proliferation of thymocytes was demonstrated when PHE were administrated with Con A than Con A alone. Such effect on thymocyte was not observed when PHE was used alone. (2) Proliferation of spleen lymphocytes was also stimulated when PHE were taken together with lipopolysaccharide, which was 50% and 3 times stronger than that of using lipopolysaccharide and PHE alone respectively.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Basidiomycota* / chemistry
  • Cells, Cultured
  • Drugs, Chinese Herbal / chemistry
  • Lymphocyte Activation / drug effects*
  • Male
  • Mice
  • Polysaccharides / pharmacology*
  • Spleen / cytology
  • T-Lymphocytes / drug effects


  • Drugs, Chinese Herbal
  • Polysaccharides