TGF-beta related genes in development

Curr Opin Genet Dev. 1994 Aug;4(4):517-22. doi: 10.1016/0959-437x(94)90066-c.


Embryonic induction is the process by which signals from one cell population change the developmental fate of another. Polypeptides related to growth factors are one group of molecules mediating many inductive events. Recent data on the embryonic expression and function of signaling proteins related to transforming growth factor beta, in both vertebrate and invertebrate systems, have shown that these molecules play important roles in both pattern formation and tissue specification during embryogenesis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • 3T3 Cells
  • Animals
  • Bone Morphogenetic Proteins
  • Chick Embryo
  • Drosophila / embryology
  • Drosophila Proteins*
  • Embryonic Induction / genetics*
  • Gene Expression Regulation, Developmental*
  • Genes, Regulator
  • Insect Hormones / metabolism
  • Mice
  • Morphogenesis / genetics
  • Proteins / metabolism
  • Signal Transduction
  • Transforming Growth Factor beta / genetics*
  • Transforming Growth Factor beta / metabolism*
  • Xenopus


  • Bone Morphogenetic Proteins
  • Drosophila Proteins
  • Insect Hormones
  • Proteins
  • Transforming Growth Factor beta
  • dpp protein, Drosophila