Chromosome abnormalities in breast fibroadenomas

Cancer Genet Cytogenet. 1994 Oct 15;77(2):125-8. doi: 10.1016/0165-4608(94)90227-5.


Cytogenetic analysis of 25 breast fibroadenomas (FA) showed clonal chromosome alterations in three cases. Insertion (12;?) (q15;?) and deletion (2) (q14q31 or q32) were detected as a sole change in cases 1 and 3, respectively. Case 2 displayed the karyotype 45,XX,t(1;8;16)(q25;q23;q22-23), add (7)(p14), rea(15), -17. The present findings are discussed together with the reports on FA in the literature.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Breast Neoplasms / genetics*
  • Chromosome Aberrations*
  • Fibroadenoma / genetics*
  • Humans
  • Karyotyping
  • Prohibitins