H2O2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response

Cell. 1994 Nov 18;79(4):583-93. doi: 10.1016/0092-8674(94)90544-4.

Abstract

Microbial elicitors or attempted infection with an avirulent pathogen strain causes the rapid production of reactive oxygen intermediates. We report here that H2O2 from this oxidative burst not only drives the cross-linking of cell wall structural proteins, but also functions as a local trigger of programmed death in challenged cells and as a diffusible signal for the induction in adjacent cells of genes encoding cellular protectants such as glutathione S-transferase and glutathione peroxidase. Thus, H2O2 from the oxidative burst plays a key role in the orchestration of a localized hypersensitive response during the expression of plant disease resistance.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Blotting, Northern
  • Cell Death*
  • Cells, Cultured
  • Gene Expression
  • Genes, Plant*
  • Glutathione Peroxidase / biosynthesis
  • Glutathione Transferase / biosynthesis
  • Hydrogen Peroxide / metabolism*
  • Immunity, Innate / physiology
  • Plant Diseases
  • Plasmids
  • RNA, Plant / analysis
  • RNA, Plant / metabolism
  • Respiratory Burst*
  • Signal Transduction
  • Soybeans / cytology
  • Soybeans / physiology*
  • Transcription, Genetic

Substances

  • RNA, Plant
  • Hydrogen Peroxide
  • Glutathione Peroxidase
  • Glutathione Transferase