Hartnup disease presenting in an adult

Clin Exp Dermatol. 1994 Sep;19(5):407-8. doi: 10.1111/j.1365-2230.1994.tb02694.x.


A young woman presented with pellagra. Her symptoms were precipitated by prolonged lactation and increased activity. Dietary intake of niacin was within recommended guidelines. Chromatography of urinary amino acids was diagnostic of Hartnup disease, an inherited disorder usually presenting in childhood. Her symptoms resolved with oral nicotinamide.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Dermatitis, Phototoxic / etiology*
  • Dermatitis, Phototoxic / pathology
  • Female
  • Hartnup Disease / complications*
  • Humans
  • Lactation
  • Pellagra / etiology*
  • Physical Exertion
  • Pregnancy
  • Skin / pathology