Basal ganglia-thalamocortical circuits: their role in control of movements

J Clin Neurophysiol. 1994 Jul;11(4):420-31.


The motor circuitry of the basal ganglia is organized in parallel with basal ganglia circuits involved in oculomotor, associative, and limbic functions. These circuits comprise reentrant pathways that originate in various neocortical domains and pass through the basal ganglia before returning, by way of the thalamus, to select portions of the frontal lobe. Recent progress in characterizing the anatomy and physiology of these pathways has provided new insights into the pathophysiology of basal ganglia-related movement disorders and enhanced our understanding of the normal role of the basal ganglia in movement control and adaptive motor behavior.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Basal Ganglia / physiology*
  • Brain Mapping
  • Cerebral Cortex / physiology*
  • Humans
  • Motor Neurons / physiology
  • Muscle, Skeletal / innervation*
  • Nerve Net / physiology*
  • Neural Pathways / physiology
  • Thalamic Nuclei / physiology*