Prevention of febrile seizures by dietary supplementation with N-3 polyunsaturated fatty acids

Z Spirer; L Koren; A Finkelstein; U Jurgenson

doi:10.1016/0306-9877(94)90047-7

Prevention of febrile seizures by dietary supplementation with N-3 polyunsaturated fatty acids

Med Hypotheses. 1994 Jul;43(1):43-5. doi: 10.1016/0306-9877(94)90047-7.

Authors

Z Spirer¹, L Koren, A Finkelstein, U Jurgenson

Affiliation

¹ Dana Childrens Hospital, Tel Aviv Medical Center, Israel.

PMID: 7968719
DOI: 10.1016/0306-9877(94)90047-7

Abstract

N-3 polyunsaturated fatty acids reduce the synthesis of IL-1, the main molecule responsible for fever. We speculate that this action may be used as a prophylactic in preventing febrile seizures in susceptible children.

MeSH terms

Child, Preschool
Fatty Acids, Omega-3 / administration & dosage*
Humans
Infant
Interleukin-1 / biosynthesis
Models, Biological
Recurrence
Seizures, Febrile / etiology
Seizures, Febrile / prevention & control*

Substances

Fatty Acids, Omega-3
Interleukin-1