Erythromycin in neonatal postoperative intestinal dysmotility

Arch Dis Child Fetal Neonatal Ed. 1994 Sep;71(2):F128-9. doi: 10.1136/fn.71.2.f128.


The motilin agonist erythromycin was used successfully in four infants receiving prolonged parenteral nutrition for severe intestinal dysmotility after gastrointestinal surgery. In a further child with a neuropathic intestinal pseudo-obstruction erythromycin induced a striking small intestinal manometric response, but was without effect in a child with an intestinal myopathy.

MeSH terms

  • Erythromycin / therapeutic use*
  • Gastrointestinal Motility / drug effects*
  • Humans
  • Infant, Newborn
  • Infant, Premature
  • Intestinal Diseases / drug therapy*
  • Intestine, Small / physiopathology
  • Jejunum / abnormalities
  • Manometry
  • Postoperative Complications / drug therapy*
  • Postoperative Complications / physiopathology
  • Stomach / abnormalities


  • Erythromycin