Women with epilepsy. Reproduction and effects of pregnancy on epilepsy

Neurol Clin. 1994 Aug;12(3):479-95.


Conventional wisdom and prevailing medical practice strongly support the belief that medication should be avoided during pregnancy. For the nearly one million women of childbearing age with epilepsy in the United States this is often difficult, if not impossible, and for many of these women becoming pregnant raises many conflicting issues. Women with epilepsy may face a possible increase in the frequency and severity of seizures, and in generalized tonic-clonic seizures there is a small but increased risk of miscarriage.

Publication types

  • Review

MeSH terms

  • Abnormalities, Drug-Induced / etiology
  • Anticonvulsants / administration & dosage
  • Anticonvulsants / adverse effects*
  • Anticonvulsants / blood
  • Breast Feeding
  • Dose-Response Relationship, Drug
  • Electroencephalography / drug effects
  • Epilepsy / drug therapy*
  • Epilepsy / physiopathology
  • Female
  • Humans
  • Infant, Newborn
  • Metabolic Clearance Rate / physiology
  • Pregnancy
  • Pregnancy Complications / drug therapy*
  • Pregnancy Complications / physiopathology
  • Risk Factors


  • Anticonvulsants