Modafinil Binds to the Dopamine Uptake Carrier Site With Low Affinity

Sleep. 1994 Aug;17(5):436-7. doi: 10.1093/sleep/17.5.436.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Arousal / drug effects*
  • Arousal / physiology
  • Benzhydryl Compounds / pharmacokinetics
  • Benzhydryl Compounds / pharmacology*
  • Binding, Competitive / physiology
  • Brain / drug effects*
  • Brain / physiopathology
  • Central Nervous System Stimulants / pharmacokinetics
  • Central Nervous System Stimulants / pharmacology
  • Cerebral Cortex / drug effects
  • Cerebral Cortex / physiopathology
  • Corpus Striatum / drug effects
  • Corpus Striatum / physiopathology
  • Dopamine Plasma Membrane Transport Proteins
  • Guinea Pigs
  • Humans
  • Membrane Proteins / drug effects*
  • Membrane Proteins / physiology
  • Modafinil
  • Narcolepsy / physiopathology*
  • Nerve Tissue Proteins / drug effects*
  • Nerve Tissue Proteins / physiology
  • Prosencephalon / drug effects
  • Prosencephalon / physiopathology
  • Rats
  • Receptors, Dopamine / drug effects*
  • Receptors, Dopamine / physiology

Substances

  • Benzhydryl Compounds
  • Central Nervous System Stimulants
  • Dopamine Plasma Membrane Transport Proteins
  • Membrane Proteins
  • Nerve Tissue Proteins
  • Receptors, Dopamine
  • Modafinil