Human N-methyl-D-aspartate receptor modulatory subunit hNR3: cloning and sequencing of the cDNA and primary structure of the protein

Biochim Biophys Acta. 1995 Jan 2;1260(1):105-8. doi: 10.1016/0167-4781(94)00189-a.

Abstract

Several cDNA clones encoding the human N-methyl-D-aspartate receptor modulatory subunit hNR3, were isolated from a human fetal brain library. The hNR3 cDNA demonstrated a 91.3-91.5% nucleotide (nt) identity with the rat NR2B and mouse epsilon 2 cDNAs. The nt sequence of hNR3 would encode a 1484 amino acid (aa) protein that has a 98.4-98.5% identity with the mouse epsilon 2 and rat NR2B subunits.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Brain / embryology
  • DNA, Complementary
  • Humans
  • Mice
  • Molecular Sequence Data
  • Rats
  • Receptors, N-Methyl-D-Aspartate / chemistry
  • Receptors, N-Methyl-D-Aspartate / genetics*
  • Sequence Homology, Amino Acid

Substances

  • DNA, Complementary
  • Receptors, N-Methyl-D-Aspartate

Associated data

  • GENBANK/U11287