A model-based design of a vaccination strategy against rubella in a non-immunized community of São Paulo State, Brazil

Epidemiol Infect. 1994 Jun;112(3):579-94. doi: 10.1017/s0950268800051281.


A mixed vaccination strategy against rubella is proposed. We describe how the vaccination strategy was designed with the help of mathematical techniques. The strategy was designed for application in a non-immunized community of the State of São Paulo, Brazil, and was implemented by local health authorities in 1992. This strategy comprises a pulse vaccination campaign, covering the age interval between 1 and 10 years, followed by the introduction of the vaccine in the immunization calendar at 15 months of age. The expected impact of the proposed strategy is discussed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Brazil
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Immunization Schedule
  • Infant
  • Mathematics
  • Models, Theoretical*
  • Preventive Health Services / organization & administration*
  • Rubella / immunology
  • Rubella / prevention & control*
  • Rubella Vaccine / administration & dosage*
  • Vaccination*


  • Rubella Vaccine