Sodium thiosulphate in the treatment of renal tubular acidosis I with nephrocalcinosis

Scand J Urol Nephrol. 1994 Mar;28(1):107-8. doi: 10.3109/00365599409180482.


Nephrocalcinosis is a common feature in renal tubular acidosis I (RTA-I) and contributes to renal insufficiency. We describe a patient, 37 years old, with RTA-I, mild renal failure and extended nephrocalcinosis. His disease was diagnosed in age 28 and patient is under treatment with sodium bicarbonate, potassium gluconate and sodium thiosulphate for 9 years. By this treatment nephrocalcinosis and renal function have not been worsened and patient is without clinical symptoms.

Publication types

  • Case Reports

MeSH terms

  • Acid-Base Equilibrium / drug effects
  • Acidosis, Renal Tubular / diagnostic imaging
  • Acidosis, Renal Tubular / drug therapy*
  • Adult
  • Antioxidants / therapeutic use*
  • Humans
  • Kidney Calculi / diagnostic imaging
  • Kidney Calculi / drug therapy*
  • Long-Term Care
  • Male
  • Nephrocalcinosis / diagnostic imaging
  • Nephrocalcinosis / drug therapy*
  • Radiography
  • Thiosulfates / therapeutic use*


  • Antioxidants
  • Thiosulfates
  • sodium thiosulfate