L4-5 degenerative spondylolisthesis in monozygous twins

Spine (Phila Pa 1976). 1994 Apr 15;19(8):985-6. doi: 10.1097/00007632-199404150-00019.


Objective: The author reports symptomatic spinal canal stenosis due to degenerative spondylolisthesis at L4-5 in identical twins.

Summary of background data: The patient reported his brother had a similar condition.

Methods: Monozygosity was established by phenotyping.

Conclusions: Spinal morphology and degenerative disease may be genetically determined.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Diseases in Twins / genetics*
  • Humans
  • Lumbar Vertebrae / diagnostic imaging*
  • Male
  • Radiography
  • Spondylolisthesis / diagnostic imaging
  • Spondylolisthesis / genetics*
  • Twins, Monozygotic*