Tissue plasminogen activator thrombolysis and transluminal angioplasty in the treatment of basilar artery thrombosis: case report

Surg Neurol. 1994 May;41(5):358-61. doi: 10.1016/0090-3019(94)90026-4.


A 61-year-old man with basilar artery thrombotic occlusion was successfully treated by a combination of local infusion of tissue plasminogen activator (t-PA) followed by percutaneous transluminal angioplasty (PTA). t-PA superselective infusion combined with the mechanical destruction of the clot by the guide wire was effective for recanalization. A Stealth dilation catheter, with a 2.5-mm balloon diameter and 10-mm length, was used for PTA. A balloon inflation time of 60 seconds with 4 atmospheres of pressure was delivered for successful dilation of the basilar artery. It was confirmed to be widely patent on follow-up angiography 40 days after the combined procedure with no further ischemic attacks apparent on clinical examination at 6 months.

Publication types

  • Case Reports

MeSH terms

  • Angioplasty, Balloon*
  • Basilar Artery*
  • Combined Modality Therapy
  • Humans
  • Male
  • Middle Aged
  • Thrombolytic Therapy*
  • Thrombosis / drug therapy
  • Thrombosis / therapy*
  • Tissue Plasminogen Activator / therapeutic use*


  • Tissue Plasminogen Activator