Comparison of 0.25% desoxymethasone ointment with 0.05% fluocinonide ointment in psoriasis

Curr Med Res Opin. 1976;4(10):703-5. doi: 10.1185/03007997609112005.

Abstract

A double-blind comparative trial was carried out in 56 patients with psoriasis to assess the effectiveness of 0.25% desoxymethasone and 0.05% fluocinonide ointments. All patients showed marked improvement in their condition with twice daily application of the ointments during the 2-week period of the trial. Erythema, scaling and induration on the desoxymethasone-treated side showed a significantly better improvement than on the fluocinonide-treated side.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Clinical Trials as Topic
  • Dexamethasone / administration & dosage
  • Dexamethasone / analogs & derivatives*
  • Dexamethasone / therapeutic use*
  • Double-Blind Method
  • Female
  • Fluocinolone Acetonide / analogs & derivatives*
  • Fluocinonide / administration & dosage
  • Fluocinonide / therapeutic use*
  • Humans
  • Male
  • Middle Aged
  • Ointments
  • Psoriasis / drug therapy*
  • Psoriasis / pathology
  • Skin / pathology

Substances

  • Ointments
  • Fluocinolone Acetonide
  • Fluocinonide
  • Dexamethasone