Abstract
The pineal principle, melatonin, was administered to 4 Parkinsonian patients. Hypothalam0-pituitary-adrenal function tests were performed before and after 4 weeks of treatment. At a maximum dosage of 1 g daily no impairment of H-P-A function was detected.
MeSH terms
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Adrenal Glands / physiopathology*
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Circadian Rhythm
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Clinical Trials as Topic
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Female
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Humans
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Hydrocortisone / blood
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Hypothalamus / physiopathology*
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Male
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Melatonin / metabolism
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Melatonin / therapeutic use*
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Middle Aged
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Parkinson Disease / drug therapy*
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Parkinson Disease / metabolism
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Parkinson Disease / physiopathology
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Pituitary Gland / physiopathology*
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Steroids / urine
Substances
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Steroids
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Melatonin
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Hydrocortisone