Sequence of the fruB Gene of Escherichia Coli Encoding the Diphosphoryl Transfer Protein (DTP) of the Phosphoenolpyruvate: Sugar Phosphotransferase System

FEMS Microbiol Lett. 1994 May 1;118(1-2):159-62. doi: 10.1111/j.1574-6968.1994.tb06819.x.


The Escherichia coli genome sequencing project in the 47 to 48 centisome region has resulted in the sequencing of the complete fructose operon (fruBKA). Due to a single base insertion, the presence of the fruB gene went unnoticed. The revised nucleotide sequence of the fruB gene, the deduced amino acid sequence of its protein product, the diphosphoryl transfer protein of the phosphoenolpyruvate: sugar phosphotransferase system, and putative transcriptional regulatory signals of the fru operon of E. coli are here presented and compared with that from Salmonella typhimurium.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Bacterial Proteins*
  • Base Sequence
  • Binding Sites
  • Carrier Proteins / chemistry
  • Carrier Proteins / genetics*
  • Databases, Factual
  • Escherichia coli / enzymology
  • Escherichia coli / genetics*
  • Escherichia coli Proteins*
  • Frameshift Mutation
  • Genes, Bacterial / genetics*
  • Intracellular Signaling Peptides and Proteins
  • Molecular Sequence Data
  • Open Reading Frames
  • Phosphoenolpyruvate Sugar Phosphotransferase System / chemistry*
  • Protein Kinases
  • Sequence Alignment
  • Sequence Analysis, DNA


  • Bacterial Proteins
  • Carrier Proteins
  • Escherichia coli Proteins
  • Intracellular Signaling Peptides and Proteins
  • fructose-induced HPr-like protein, bacteria
  • Protein Kinases
  • fruB protein, E coli
  • Phosphoenolpyruvate Sugar Phosphotransferase System

Associated data

  • GENBANK/S72443