Cytologically proven seronegative Lyme choroiditis and vitritis

Retina. 1994;14(1):39-42. doi: 10.1097/00006982-199401000-00009.


Purpose: To report on a vitreous specimen in a 53-year-old patient with unilateral choroiditis and vitritis of unknown cause.

Methods: Cytologic examination of a vitreous aspirate stained by the Papanicolaou method.

Results: Intravitreal spirochetes consistent with Borrelia burgdorferi were found in this seronegative patient.

Conclusion: Vitreous specimens of patients with choroiditis and vitritis of unknown cause should be examined cytologically, particularly when serologic results do not corroborate the clinical findings of Lyme disease.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Bacterial / analysis
  • Borrelia burgdorferi Group / immunology
  • Borrelia burgdorferi Group / isolation & purification
  • Choroiditis / diagnosis*
  • Choroiditis / microbiology
  • Enzyme-Linked Immunosorbent Assay
  • Eye Infections, Bacterial / diagnosis*
  • Female
  • Humans
  • Immunoglobulin G / analysis
  • Lyme Disease / diagnosis*
  • Middle Aged
  • Visual Acuity
  • Vitreous Body / microbiology*


  • Antibodies, Bacterial
  • Immunoglobulin G