Identification of a gene encoding a new Ypt/Rab-like monomeric G-protein in Saccharomyces cerevisiae

Yeast. 1994 Mar;10(3):399-402. doi: 10.1002/yea.320100313.

Abstract

A Saccharomyces cerevisiae sequence cloned by serendipity was found to encode a protein that is a new member of the Ypt/Rab monomeric G-protein family. This sequence shows high homology to the yeast genes SEC4 and YPT1 and, like SEC4 and YPT1, is essential for viability. The sequence was localized to chromosome V based upon hybridization to pulse-field gel-separated yeast chromosomes. The sequence has been deposited in the GenBank data library under Accession Number L17070.

Publication types

  • Comparative Study

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Chromosome Mapping
  • GTP-Binding Proteins / genetics*
  • Genes, Fungal / genetics*
  • Genes, Lethal / genetics
  • Genes, ras / genetics
  • Molecular Sequence Data
  • Protein Conformation
  • Saccharomyces cerevisiae / genetics*
  • Saccharomyces cerevisiae Proteins*
  • Sequence Homology, Amino Acid
  • rab GTP-Binding Proteins*

Substances

  • Saccharomyces cerevisiae Proteins
  • YPT31 protein, S cerevisiae
  • GTP-Binding Proteins
  • YPT1 protein, S cerevisiae
  • SEC4 protein, S cerevisiae
  • rab GTP-Binding Proteins

Associated data

  • GENBANK/L17070