[Transfer of photosensitive epilepsy of genetic origin by selective grafts of brain vesicles in chick embryo]

C R Seances Soc Biol Fil. 1993;187(3):384-9.
[Article in French]

Abstract

We transferred the avian photosensitive genetic epilepsy to normal chicken by transplanting at least prosencephalic and mesencephalic vesicles from epileptic to normal chick embryos at day 2 of incubation. Chimeras showed typical interictal EEG and developed, under intermittent light stimulation, seizures phenotypically and electrically similar to the epileptic strain seizures.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Chick Embryo
  • Epilepsy / genetics*
  • Light
  • Mesencephalon / transplantation*
  • Prosencephalon / transplantation*
  • Rhombencephalon / transplantation
  • Transplantation Chimera