Nasopharyngeal carcinoma among the population in Jerusalem

Am J Otolaryngol. May-Jun 1994;15(3):190-2. doi: 10.1016/0196-0709(94)90003-5.


Purpose: Because the incidence of nasopharyngeal carcinoma differs in various ethnic groups, the heterogeneous population of Jerusalem was selected for an epidemiologic study.

Materials and methods: Data from 63 consecutive patients diagnosed with nasopharyngeal carcinoma were collected in a retrospective manner. Information regarding sex, age, ethnic origin, tobacco and alcohol consumption, chronic sinusitis, and immunoglobulin (Ig)G to Epstein-Barr virus capsid antigen was tabulated and was statistically analyzed by the z test.

Results: The results showed an increased incidence of disease in the Sephardi Jews, especially of Moroccan origin. The histologic type was 100% poorly differentiated squamous carcinoma, and was associated with a better prognosis than is usually seen in the literature.

Conclusion: This study identified an ethnic-related pattern of nasopharyngeal carcinoma in Jerusalem, and found a 100% incidence of poorly differentiated squamous carcinoma, and a better survival rate than the literature suggests, which may be attributable to the histologic type.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Antibodies, Viral / blood
  • Capsid / immunology
  • Carcinoma, Squamous Cell / epidemiology*
  • Carcinoma, Squamous Cell / ethnology
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / therapy
  • Ethnic Groups
  • Female
  • Herpesvirus 4, Human / immunology
  • Humans
  • Incidence
  • Israel / epidemiology
  • Jews
  • Male
  • Middle Aged
  • Morocco / ethnology
  • Nasopharyngeal Neoplasms / epidemiology*
  • Nasopharyngeal Neoplasms / ethnology
  • Nasopharyngeal Neoplasms / pathology
  • Nasopharyngeal Neoplasms / therapy
  • Neoplasm Staging
  • Retrospective Studies
  • Survival Rate


  • Antibodies, Viral