Prevalence of antibodies to herpes simplex virus in pregnant women in Stockholm in 1969, 1983 and 1989: implications for STD epidemiology

Int J STD AIDS. Mar-Apr 1994;5(2):113-6. doi: 10.1177/095646249400500207.

Abstract

Prevalence of antibody to herpes simplex virus types 1 and 2 was assessed in consecutive serum samples from a total of 3700 women pregnant in 1969, 1983, or 1989 from the same catchment area in Stockholm. There was little change in seroprevalence of antibody to herpes simplex type 1 in the 3 groups, but age-adjusted herpes simplex virus type 2 antibody prevalence was 19, 33, and 33% respectively. Increase in type 2 seropositivity with age was slight and similar in 1969 and 1989, but steep in 1983, indicating a shift in sexual behaviour. However, rising prevalence in women will be mirrored by rising prevalence in their male partners. The increase from 1969 to 1989 will thus partly be due to higher risk of infection per partner, and cannot be taken as direct evidence of increased rate of partner change during this 20-year period.

MeSH terms

  • Adult
  • Age Factors
  • Antibodies, Viral / blood*
  • Female
  • Herpes Genitalis / blood
  • Herpes Genitalis / epidemiology*
  • Herpes Genitalis / microbiology
  • Herpesvirus 1, Human / immunology*
  • Herpesvirus 2, Human / immunology*
  • Humans
  • Longitudinal Studies
  • Male
  • Population Surveillance*
  • Pregnancy
  • Pregnancy Complications, Infectious / blood
  • Pregnancy Complications, Infectious / epidemiology*
  • Pregnancy Complications, Infectious / microbiology
  • Prevalence
  • Sampling Studies
  • Seroepidemiologic Studies
  • Sexual Behavior
  • Sexual Partners
  • Sexually Transmitted Diseases / blood
  • Sexually Transmitted Diseases / epidemiology*
  • Sexually Transmitted Diseases / microbiology
  • Sweden / epidemiology
  • Urban Population

Substances

  • Antibodies, Viral