A case of meningioangiomatosis without von Recklinghausen's disease. Report of a case and review of 13 cases

Childs Nerv Syst. 1994 Mar;10(2):126-30. doi: 10.1007/BF00302777.


Meningioangiomatosis is rare disease and is classified as hamartoma in central neurofibromatosis. Unlike most cases of meningioangiomatosis, the very rare case reported here was not associated with von Recklinghausen's disease. We could find only 12 previous cases reported in the literature. A review was carried out of the clinical features, imaging characteristics, and histopathological findings in those 12 plus ours for a total 13 cases. Several types of convulsion were identified as clinical symptoms in 11 of the 13 cases. They were treated surgically. Prognosis was satisfactory in most cases. Proliferation of small blood vessels accompanied by endothelial cells with glial tissue as background and proliferation of fibroblasts or meningothelial cells in the perivascular space were observed to be the most frequent histopathological features.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Biomarkers, Tumor / analysis
  • Craniotomy
  • Frontal Lobe / pathology
  • Frontal Lobe / surgery
  • Humans
  • Male
  • Meningioma / diagnosis*
  • Meningioma / pathology
  • Meningioma / surgery
  • Neurofibromatosis 1 / diagnosis*
  • Neurofibromatosis 1 / pathology
  • Neurofibromatosis 1 / surgery
  • Neuroglia / pathology
  • Neurologic Examination
  • Neurons / pathology
  • Phosphopyruvate Hydratase / analysis
  • S100 Proteins / analysis


  • Biomarkers, Tumor
  • S100 Proteins
  • Phosphopyruvate Hydratase