Cefotetan-induced hemolytic anemia causing severe hypophosphatemia

Am J Hematol. 1994 Aug;46(4):369-70. doi: 10.1002/ajh.2830460422.


Phosphorus is a major component of proteins, phospholipids, and nucleotides. The increased uptake of phosphorus by cells during erythropoiesis can result in severe hypophosphatemia. A case of severe hypophosphatemia due to accelerated erythropoiesis in response to Cefotetan-induced hemolytic anemia is described. The hypophosphatemia seen during hemolysis may be the result, rather than the cause, of the hemolysis.

Publication types

  • Case Reports

MeSH terms

  • Anemia, Hemolytic / complications*
  • Anemia, Hemolytic / etiology*
  • Anemia, Hemolytic / physiopathology
  • Cefotetan / adverse effects*
  • Erythropoiesis / drug effects
  • Female
  • Humans
  • Hypophosphatemia / etiology*
  • Middle Aged


  • Cefotetan