Persistent hyperaminotransferasemia resolving after weight reduction in obese children

J Pediatr. 1994 Aug;125(2):239-41. doi: 10.1016/s0022-3476(94)70202-0.


Nine obese children were referred to our liver disease unit because of asymptomatic, long-standing (range, 4 to 49 months) hyperaminotransferasemia of unknown origin. Ultrasonography showed a "bright" liver in most patients. A hypocaloric diet was prescribed, and the hepatic abnormalities of the complaint patients showed a prompt and persistent improvement that paralleled the loss of excess weight.

MeSH terms

  • Alanine Transaminase / blood*
  • Aspartate Aminotransferases / blood*
  • Child
  • Child, Preschool
  • Fatty Liver / etiology*
  • Female
  • Humans
  • Male
  • Obesity / blood*
  • Obesity / complications
  • Obesity / diet therapy
  • Weight Loss / physiology*


  • Aspartate Aminotransferases
  • Alanine Transaminase