Resting energy expenditure and body composition in morbidly obese, obese and control subjects

Acta Diabetol. 1994 Apr;31(1):47-51. doi: 10.1007/BF00580761.


Resting energy expenditure (REE) was investigated by indirect calorimetry in relation to body composition and to different degrees of obesity in order to assess if a defective energy expenditure contributes to extra body fat accumulation. Differences were found between control subjects (group C; BMI 23 +/- 0.5 kg/m2, REE 5890 +/- 218 kJ/day; mean +/- SEM) and obese subjects (group O; BMI 34.2 +/- 0.9 kg/m2, REE 7447 +/- 360 kJ/day; P < 0.0001) and between group C and morbidly obese subjects (group MO; BMI 49.9 +/- 1.6 kg/m2, REE 8330 +/- 360 kJ/day; P < 0.0001); REE was not significantly different between groups O and MO. Body composition data were obtained by means of body impedance analysis. Even though group MO had a fat mass higher than group O, body cell mass, the metabolically active body compartment, was similar in groups O and MO, and this fact may have contributed to the similar REE in the two groups. Multiple regression analysis gave the following equation as the best predictor of REE: REE (kJ/day) = 1591 +/- 49BW + 74BCM - 737G (R2 = 0.88), where BW is body weight, BCM is body cell mass and G is a dummy variable coding group membership (group C = 1; group O = 2; group MO = 3). Thus the analysis showed a negative impact of obesity on REE beyond body composition variables.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Basal Metabolism / physiology*
  • Body Composition / physiology*
  • Body Height / physiology
  • Body Mass Index
  • Body Water / physiology
  • Body Weight / physiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Obesity / physiopathology*
  • Obesity, Morbid / physiopathology*
  • Regression Analysis