Iron acquisition in microbial pathogenesis

Trends Microbiol. 1993 May;1(2):66-9. doi: 10.1016/0966-842x(93)90036-q.


Successful competition for iron by potential pathogens is essential to establish infection. The roles of the various types of microbial iron acquisition systems in host-pathogen interactions depend on the nature of the infection and the location of the pathogen within the host. Microbes infecting the extracellular spaces of the host employ different strategies for iron acquisition than those that invade and multiply within host cells.

Publication types

  • Review

MeSH terms

  • Animals
  • Bacteria / metabolism*
  • Bacteria / pathogenicity
  • Bacterial Infections / etiology
  • Fungi / metabolism*
  • Fungi / pathogenicity
  • Ion Transport
  • Iron / metabolism*
  • Mycoses / etiology
  • Virulence


  • Iron