Abstract
A major function of the immune response is the discrimination of self from nonself. It is this response that must be overcome in transplant rejection. Progress in understanding these basic immune mechanisms has helped to improve clinical outcome and lays the foundation for a new generation of therapies.
Publication types
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Graft Rejection / classification
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Graft Rejection / immunology
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Graft Rejection / prevention & control
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Graft Survival / immunology
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HLA Antigens / immunology
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Histocompatibility Testing / methods
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Humans
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Immunity, Cellular / immunology
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Immunosuppression Therapy / methods
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Receptors, Antigen, T-Cell / immunology
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T-Lymphocytes / immunology
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Transplantation Immunology / drug effects
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Transplantation Immunology / immunology*
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Transplantation, Heterologous / methods
Substances
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HLA Antigens
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Receptors, Antigen, T-Cell