Severe hypotension, bronchospasm, and urticaria from intravenous indigo carmine

Urology. 1994 Aug;44(2):271-2. doi: 10.1016/s0090-4295(94)80149-5.

Abstract

Indigo carmine is generally believed to be a safe, biologically inert substance. Adverse reactions to the intravenous administration of this dye have been seen only rarely. We report a life-threatening anaphylactoid reaction to indigo carmine that may have been due to either a drug allergy or to its intrinsic serotonergic properties.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Bronchial Spasm / chemically induced*
  • Bronchial Spasm / complications
  • Drug Eruptions / complications
  • Drug Eruptions / etiology*
  • Humans
  • Hypotension / chemically induced*
  • Hypotension / complications
  • Indigo Carmine / administration & dosage
  • Indigo Carmine / adverse effects*
  • Injections, Intravenous
  • Male
  • Severity of Illness Index
  • Urticaria / chemically induced*
  • Urticaria / complications

Substances

  • Indigo Carmine