The Sterrad Sterilization System by Advanced Sterilization Products (ASP) exploits the synergism between peroxide and low temperature gas plasma (an excited or ionized gas) to rapidly destroy microorganisms (Figure 1). At the completion of the sterilization process based on this technology, no toxic residues remain on the sterilized items. The technology is particularly suited to the sterilization of heat and moisture sensitive instruments since process temperatures do not exceeded about 50 degrees C (140 degrees F) and sterilization occurs in a low moisture environment. Total process time is about one hour. The efficacy of the process has been demonstrated against a broad spectrum or microorganisms and on a large number of substrates used in medical instruments.