Evening primrose oil and marine oil in the treatment of psoriasis

Clin Exp Dermatol. 1994 Mar;19(2):127-9. doi: 10.1111/j.1365-2230.1994.tb01139.x.


The effect of dietary supplementation with a combination of n-3 (marine oil) and n-6 (evening primrose oil) essential fatty acids in the treatment of chronic stable plaque psoriasis was observed. Thirty-seven patients in a double-blind parallel trial were studied. There was no significant improvement in clinical severity of psoriasis or change in transepidermal water loss.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
  • Combined Modality Therapy
  • Dermatologic Agents / therapeutic use*
  • Double-Blind Method
  • Fatty Acids, Essential / therapeutic use*
  • Fish Oils / therapeutic use*
  • Humans
  • Linoleic Acids
  • Middle Aged
  • Plant Oils
  • Psoriasis / therapy*
  • gamma-Linolenic Acid


  • Anti-Inflammatory Agents, Non-Steroidal
  • Dermatologic Agents
  • Fatty Acids, Essential
  • Fish Oils
  • Linoleic Acids
  • Plant Oils
  • evening primrose oil
  • gamma-Linolenic Acid